For the first 7 years, we were called the Vanderbilt Center for Clinical Cardiovascular Outcomes Research and Trials Evaluation (V-CREATE) team, lead by Dr. Matthew Freiberg.
Since July of 2014, the V-CREATE team has received 10 new R01/U01 grants, a new P01 center grant, a new K12 training program and has published 97 manuscripts in journals such as Journal of the American Medical Association, British Medical Journal, Circulation, JAMA cardiology, Journal of the National Cancer Institute, American Journal of Respiratory and Critical Care Medicine, Lancet HIV, and Nature Medicine. Additionally, we have donated time and effort to help other investigators at VUMC. Presently, we are contributing to nine unfunded research projects including seven R01 grant applications and possibly a new program project grant. These projects represent faculty from across VUMC including the departments of medicine and surgery and the VICC. Our evolution as a population science and clinical trials center started with individual grants focused on HIV and cardiovascular disease. Phase two began when we received a K12 NHLBI training grant designed to train the next generation of investigators with expertise in HIV and heart, lung, blood, and sleep disease and a P01 center grant. Presently, we are also embarking on Phase 3, which will leverage a unique resource with in the Veteran Affairs (the 16.5 million participant Veterans Cohort) to create an institutional resource. We have already received NIH, AHA, and VA funding to leverage this cohort to study pulmonary hypertension in heart failure, peripheral artery disease, and COVID-19. We believe this resource will allow us to realize our vision and work with others to accomplish our mission
About Us
Our Vision
A world where any disease can be rapidly, efficiently, and thoroughly studied so therapies and cures quickly follow
Our Mission
To leverage large population cohorts involving millions of participants with granular mechanistic studies to design and conduct clinical trials to improve human health locally and globally and to train the next generation of population scientists/clinical trialists.